This white paper explores the growing burden of cardiovascular disease (CVD) in Egypt, where heart disease and stroke remain among the leading causes of death. The report examines the impact of major risk factors including hypertension, diabetes, obesity, smoking, physical inactivity, unhealthy dietary habits, and air pollution on cardiovascular health. It also reviews demographic trends, regional healthcare disparities, and the increasing prevalence of metabolic disorders that contribute to cardiovascular mortality. Additionally, the paper highlights Egypt’s national public health initiatives, including the 100 Million Healthy Lives campaign and the National Health Strategy 2024–2030, which aim to improve prevention, early detection, and management of cardiovascular risk factors. The report further discusses future projections for cardiovascular disease and explores innovative nutritional support strategies designed to promote heart health, improve cellular energy production, and support long-term cardiovascular wellness.